Publicaciones

Ortega Y, Torrealba D, Gallardo J, Fernández F, Figueroa C, Bustos P, Conejeros P, Dixon B, Mancilla M. 2026. Pathogen coinfections in wild and farmed salmonids: A systematic review. Fish & Shellfish Immunology, doi.org/10.1016/j.fsi.2026.111155

Salinas N, Torrealba D, Ahumada A, Figueroa C, Gallardo-Matus J. 2025. Cell lines and primary cultures uses for vaccine development for bacterial pathogens of fish: A systematic review. Fish & Shellfish Immunology, doi.org/10.1016/j.fsi.2025.110625

Torrealba D, López D, Zelada P, Salinas-Parra N, Valenzuela-Avilés P, García-Fruitós E, Arís A, Mercado L, Altamirano C, Gallardo J. 2024. Immunomodulation evidence of nanostructured recombinant proteins in salmonid cells, Animals, doi.org/10.3390/ani14060844

Torrealba D, Morales-Lange B, Mulero V, Mercado L, Gallardo J. 2023. Heritability of immunity traits and resistance of Atlantic salmon against the sea louse Caligus rogercresseyi, Biology,  doi.org/10.3390/biology12081078 

Haddad F, Soliman A, Wong M, Albers E, Semple S, Torrealba D, Heimroth R, Tierney K, Nashiry A, Tierney K, Barreda D. 2023. Fever integrates antimicrobial defences, inflammation control, and tissue repair in a cold-blooded vertebrate. eLife,  doi.org/10.7554/eLife.83644

Valenzuela P*, Torrealba D*, Figueroa C, Mercado L, Dixon B, Conejeros P, Gallardo J. 2022. Why vaccines fail against Piscirickettsiosis in farmed salmon and trout and how avoid it: A review. Frontiers in Immunology, doi.org/10.3389/fimmu.2022.1019404 (*These authors share the first authorship).

Figueroa C*, Torrealba D*, Morales-Lange B, Mercado L, Dixon B, Conejeros P, Silva G, Soto C, Gallardo J. 2022. Commercial vaccines do not confer protection against two genogroups of Piscirickettsia salmonis, LF-89 and EM-90, in Atlantic Salmon. Biology,  doi.org/10.3390/biology11070993 (*These authors share the first authorship).

Lu X, Deng Q, Thompson KD, editores. 2021. The Function of Phagocytes in Non-Mammals. More J, Torrealba D, Thomson C, Wakaruk J, Barreda D. 2020. Differential effects of drinking water quality on the immune responses of broiler chickens against fungal and bacterial challenges. Lausanne: Frontiers Media SA, doi.org/10.3389/978-2-88966-438-2

Grayfer L, DeWitte S, Edholm E, editores. 2020. Innate Immunity in Aquatic Vertebrates. Torrealba D, More J, Wakaruk J, Barreda D. Innate immunity provides biomarkers of health for teleosts exposed to nanoparticles. Lausanne: Frontiers Media SA, doi.org/10.3389/978-2-88963-427-9

Figueroa C, Veloso P, Espin L, Dixon B, Torrealba D, Efalfy IS, Afonso JM, Soto C, Conejeros P, Gallardo J. 2020. Host genetic variation explains reduced protection of commercial vaccines against a bacterial pathogen in Atlantic salmon. Scientific Reports,  doi.org/10.1038/s41598-020-70847-9

Thwaite R, Berbel C, Aparicio M, Torrealba D, Pesarrodona M, Villaverde A, Borrego JJ, Manchado M, Nerea R. 2020. Nanostructured recombinant protein particles raise specific antibodies against the nodavirus NNV coat protein in sole. Fish & Shellfish Immunology,  doi.org/10.1016/j.fsi.2020.02.029

More J, Torrealba D, Thomson C, Wakaruk J, Barreda D. 2020. Differential effects of drinking water quality on the immune responses of broiler chickens against fungal and bacterial challenges. Frontiers in Immunology, doi.org/10.3389/fimmu.2020.00584

Torrealba D, More J, Wakaruk J, Barreda D. 2019. Innate immunity provides biomarkers of health for teleosts exposed to nanoparticles. Frontiers in Immunology,  doi.org/10.3389/fimmu.2018.03074.

Ji J, Torrealba D, Thwaite R, Gomez A, Parra D, Roher N. 2019. Nanostructured TNFα protein targets the zebrafish (Danio rerio) immune system through mucosal surfaces and improves the survival after Mycobacterium marinum lethal infection. Aquaculture, doi.org/10.1016/j.aquaculture.2019.05.050

Torrealba D, Balasch JC, Criado M, Tort L, Mackenzie S, Roher N. 2018. Functional evidence for the inflammatory reflex in teleosts: A novel α7 nicotinic acetylcholine receptor modulates the macrophage response to dsRNA. Developmental & Comparative Immunology, doi.org/10.1016/j.dci.2018.02.020

Thwaite R, Jie J, Torrealba D, Coll J, Sàbes M, Villaverde A, Roher N. 2018. Protein Nanoparticles Made of Recombinant Viral Antigens: A Promising Biomaterial for Oral Delivery of Fish Prophylactics. Frontiers in Immunology, doi.org/10.3389/fimmu.2018.01652

Figueroa C, Bustos P, Torrealba D, Dixon B, Soto C, Conejeros P, Gallardo J. 2017. Coinfection takes its toll: Sea lice override the protective effects of vaccination against a bacterial pathogen in Atlantic salmon. Scientific Reports, doi.org/10.1038/s41598-017-18180-6

Torrealba D, Seras-Franzoso J, Mamat U, Wilke K, Villaverde A, Roher N, Garcia-Fruitós E. 2016. Complex amyloid nanoparticles as immunostimulant-delivery platforms for fish. PLOS ONE, doi.org/10.1371/journal.pone.0164073

Torrealba D, Parra D, Seras-Franzoso J, Vallejos E, Yero D, Gibert I, Villaverde A, García-Fruitós E, Roher N. 2016. Nanostructured recombinant cytokines: a highly stable alternative to short-lived prophylactics. Biomaterials, doi.org/10.1016/j.biomaterials.2016.08.043

Ji J*, Torrealba D*, Ruyra A, Roher N. 2015. Nanodelivery systems as new tools for immunostimulant or vaccine administration: Targeting the fish immune system. Biology, doi.org/10.3390/biology4040664 (*These authors share the first authorship)

Ruyra A, Torrealba D, Morera D, Tort L, Mackenzie S, Roher N. 2015. Zebrafish liver (ZFL) cells are able to mount an anti-viral response after stimulation with Poly (I:C). Comparative Biochemistry and Physiology, Part B, doi.org/10.1016/j.cbpb.2014.12.002

Lhorenthe JP, Gallardo JA, Villanueva B, Araya A, Torrealba D, Toledo X, Neira R. 2012. Quantitative genetic basis for resistance to Caligus rogercresseyi sea lice in a breeding population of Atlantic salmon (Salmo salar). Aquaculture, 324-325, doi.org/10.1016/j.aquaculture.2011.10.046

Torrealba D, Toledo X, Gallardo J. 2011. Artificial settlement of sea lice, Caligus rogercresseyi Boxshall & Bravo, 2000 (Copepoda, Caligidae), on tissues of fish used as substrate. Crustaceana, 84(8), doi.org/10.1163/001121611X579178


Contacto

Dra. Débora Torrealba
debora.torrealba@uoh.cl

Instituto de Ciencias de la Ingeniería
Universidad de O’Higgins
Rancagua, Chile